ZNHIT1

Alternative Names: Zinc Finger HIT-Type Containing 1, ZNHIT1, Zinc Finger HIT Domain Containing 1, Zinc Finger HIT Domain-Containing Protein 1, Zinc Finger Protein, Subfamily 4A (HIT Domain Containing) Member 1, Zinc Finger Protein Subfamily 4A Member 1, Putative Cyclin G1 Interacting Protein, Cyclin-G1-Binding Protein 1, P18 Hamlet, CG1I, H_DJ0747G18.14, p18Hamlet, CGBP1.

ZNHIT1 is a member of the ZNHIT1 family and contains a solitary HIT-type zinc finger. It is responsive to DNA damage and plays a part in instigating apoptosis through the p53 pathway. ZNHIT1 interacts with MAPK11 and MAPK14 and is a component of the chromatin-remodeling SRCAP complex, which comprises SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6, and ZNHIT1. ZNHIT1 binds to NR1D2 and relieves its inhibitory influence on APOC3 transcription, while DNA binding activity remains unaltered.

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  • Sku: PSB-pro-1448-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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UniProt Listing
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Product Details

Product Description

Recombinant Human Zinc Finger HIT-Type Containing 1 (ZNHIT1) is a protein that belongs to the zinc finger family. With a molecular weight of approximately X kDa, ZNHIT1 plays a significant role in various cellular processes. Its function involves binding to specific DNA sequences, thereby regulating gene expression and participating in transcriptional regulation. This protein's importance lies in its ability to interact with other proteins and contribute to the overall functionality of the cell. Understanding the characteristics and functions of ZNHIT1 is crucial for unraveling the intricate mechanisms underlying cellular processes.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 19.9 kDa
Structure Monomer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The ZNHIT1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMVEKKTS VRSQDPGQRR VLDRAARQRR INRQLEALEN DNFQDDPHAG LPQLGKRLPQ FDDDADTGKK KKKTRGDHFK LRFRKNFQAL LEEQNLSVAE GPNYLTACAG PPSRPQRPFC AVCGFPSPYT CVSCGARYCT VRCLGTHQET RCLKWTV.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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ZNHIT1
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