ZMAT3

Alternative Names: Zinc Finger Matrin-Type 3, Zinc Finger Protein WIG1, P53 Target Zinc Finger Protein, P53-Activated Gene 608 Protein, WIG1.

ZMAT3 possesses a nuclear localization signal and exhibits 3 zinc finger domains. Its gene's mRNA and protein expression are increased by wildtype p53. Overexpression of ZMAT3 leads to tumor cell proliferation, suggesting its involvement in the p53-dependent growth regulatory pathway. Alternative splicing of ZMAT3 gives rise to two transcript variants that encode isoforms differing by a single amino acid.

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  • Sku: PSB-pro-1635-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Zinc Finger, Matrin-Type 3 is a protein derivative that belongs to the zinc finger family. With a weight of approximately [insert weight], this protein plays a significant role in various cellular processes. Its structure comprises zinc finger motifs, which facilitate DNA binding and transcriptional regulation. This recombinant protein is widely utilized in scientific research to investigate gene expression, DNA repair mechanisms, and protein-protein interactions. Its precise and controlled use aids in advancing our understanding of cellular functioning and disease mechanisms.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
34.4 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The ZMAT3 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 2mM DTT and 50% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMILLQHA VLPPPKQPSP SPPMSVATRS TGTLQLPPQK PFGQEASLPL AGEEELSKGG EQDCALEELC KPLYCKLCNV TLNSAQQAQA HYQGKNHGKK LRNYYAANSC PPPARMSNVV EPAATPVVPV PPQMGSFKPG GRVILATEND YCKLCDASFS SPAVAQAHYQ GKNHAKRLRL AEAQSNSFSE SSELGQRRAR KEGNEFKMMP NRRNMYTVQN NSAGPYFNPR SRQRIPRDLA MCVTPSGQFY CSMCNVGAGE EMEFRQHLES KQHKSKVSEQ RYRNEMENLG YV

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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ZMAT3

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