YWHAG His

Alternative Names: YWHAG, 14-3-3 protein gamma, Protein kinase C inhibitor protein 1, KCIP-1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide.

The 14-3-3 family proteins are crucial regulators in signal transduction, checkpoint control, apoptosis, and nutrient-sensing pathways. These proteins are widely expressed and highly conserved throughout different species. Among the seven isoforms identified in mammals, 14-3-3gamma was initially believed to be specific to the brain and neurons. However, it has been found to interact with RAF1 and protein kinase C, which are involved in diverse signal transduction pathways.

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  • Sku: PSB-pka-262-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Tyr-3/Trp-5 Monooxygenase Activation Protein, Gamma His Tag is a protein that belongs to the monooxygenase activation protein family. It plays a significant role in the regulation of tyrosine hydroxylase and tryptophan hydroxylase, key enzymes involved in the biosynthesis of catecholamines and serotonin, respectively. With a molecular weight of [insert weight], this protein is commonly used in research and biotechnological applications to study the mechanisms underlying neurotransmitter synthesis and related disorders. Its importance lies in its ability to modulate the activity of these crucial enzymes, making it a valuable tool for scientific investigations.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation YWHAG solution containing 1x PBS and 50% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

Check Uniprot Link

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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YWHAG His
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