VWA2

Alternative Names: A domain-containing protein similar to matrilin and collagen, Colon cancer secreted protein 2, AMACO, CCSP-2.

Von Willebrand Factor A Domain Containing 2 (VWA2) is an extracellular matrix protein with vWA-like domains. It has a signal peptide sequence, an N-terminal VWA domain, followed by 2 vWA domains connected by a cysteine-rich sequence, and a C-terminal EGF-like domain. The expression of VWA2 is increased in stage II, III, and IV colon cancers and colon adenomas. It is considered a potential serum marker for early-stage colon cancer diagnosis.

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  • Sku: PSB-pro-2752-100µg
  • Vendor: ProSpec-Tany
$900.00 USD
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Title

Product Details

Product Description

Recombinant Human Von Willebrand Factor A Domain Containing 2 (VWA2) is a protein that belongs to the VWA domain-containing family. With a molecular weight of approximately X kDa, VWA2 plays a significant role in various biological processes. This protein is involved in cell adhesion, signal transduction, and protein-protein interactions. Understanding the function and structure of VWA2 is crucial for unraveling its physiological significance and potential therapeutic applications.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
19.3 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The VWA2 protein solution contains 20mM Tris-HCl, pH 8.0, 0.8M Urea & 50% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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VWA2

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