VEGF, CHO

Alternative Names: Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609.

Vascular endothelial growth factor (VEGF) is a significant protein involved in vasculogenesis and angiogenesis. While its main effects are observed in vascular endothelial cells, VEGF also impacts other cell types such as monocytes/macrophages, neurons, cancer cells, and kidney epithelial cells. VEGF has multiple functions including increasing vascular permeability, promoting angiogenesis, vasculogenesis, and endothelial cell growth, facilitating cell migration, and inhibiting apoptosis. In laboratory settings, VEGF has been found to stimulate endothelial cell division and migration. Additionally, VEGF acts as a vasodilator, increases microvascular permeability, and was initially referred to as vascular permeability factor. High levels of VEGF are associated with POEMS syndrome (also known as Crow-Fukase syndrome), and mutations in the VEGF gene have been linked to both proliferative and nonproliferative diabetic retinopathy.

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  • Sku: PSB-cyt-260-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Vascular Endothelial Growth Factor, CHO, is a bioengineered protein that belongs to the family of vascular endothelial growth factors (VEGFs). This protein is produced using Chinese Hamster Ovary (CHO) cells as the expression system. With a molecular weight of approximately X kilodaltons, Recombinant Human Vascular Endothelial Growth Factor, CHO, plays a significant role in promoting angiogenesis and vascular permeability. Its precise and controlled production ensures its suitability for various scientific and medical applications.

Current Lead Time

7-14 Days

Product Specifications

Species
 CHO
Expression System CHO
Purity 97.0% by SDS-PAGE
Activity
 The protein was tested in HUVEC cells, the ED50 for this effect was found to be 2-6ng/ml. The protein was tested in HUVEC cells, the ED50 for this effect was found to be 2-6ng/ml.
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation The protein was lyophilized from a Phosphate- Buffered Saline, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

Check Uniprot Link

Storage Instruction

Lyophilized Vascular Endothelial Growth Factor Human although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution VEGF Human Recombinant should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Vascular Endothelial Growth Factor Human in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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VEGF, CHO
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