Urokinase

Alternative Names: Urokinase, Abbokinase, Urokinase-type Plasminogen Activator, UK, EC 3.4.21.73, uPA.

Urokinase (UK) is a serine protease and plasminogen activator. It plays a role in various biological processes such as fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing. UK can be derived from human urine or kidney cell culture.

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  • Sku: PSB-enz-264-100µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Human Urokinase, a serine protease, is a naturally occurring enzyme that plays a significant role in the fibrinolytic system. Belonging to the family of plasminogen activators, it is responsible for the conversion of plasminogen to plasmin, a key enzyme involved in the dissolution of blood clots. With a molecular weight of approximately 54 kilodaltons, human urokinase exhibits a specific affinity towards fibrin, facilitating the breakdown of fibrin clots and promoting clot lysis. Its enzymatic activity is regulated by various physiological factors, making it a crucial component in maintaining the delicate balance of hemostasis.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Human Urine
Purity 90.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The Urokinase was lyophilized from a concentrated (1mg/ml) solution containing phosphate buffer.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Lyophilized Urokinase although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Urokinase should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Urokinase in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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Urokinase

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