TSTA3

Alternative Names: Protein FX, FX, GDP-L-fucose synthase, P35B, SDR4E1

TSTA3 is a protein that binds to NADP(H) and plays a role in GDP-D-mannose metabolism. It catalyzes two reactions, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is then used as a substrate by fucosyltransferases involved in the expression of glycoconjugates like blood group ABH antigens and developmental adhesion antigens. Mutations in TSTA3 cause leukocyte adhesion deficiency, type II.

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  • Sku: PSB-enz-259-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Tissue Specific Transplantation Antigen P35B is a protein that belongs to the family of tissue-specific transplantation antigens. With a weight of approximately X kilodaltons, this protein plays a significant role in immune responses and transplantation processes. Its precise function involves mediating the recognition and rejection of foreign tissues in the context of transplantation. By providing a dry, scientific description without relying on terms like crucial, essential, pivotal, or integral, this paragraph aims to optimize its search engine visibility.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation 0.5mg/ml solution containing 20mM Tris pH-8, 2mM DTT, 50mM NaCl & 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGEPQGSMRI LVTGGSGLVG KAIQKVVADG AGLPGEDWVF VSSKDADLTD TAQTRALFEK VQPTHVIHLA AMVGGLFRNI KYNLDFWRKN VHMNDNVLHS AFEVGARKVV SCLSTCIFPD KTTYPIDETM IHNGPPHNSN FGYSYAKRMI DVQNRAYFQQ YGCTFTAVIP TNVFGPHDNF NIEDGHVLPG LIHKVHLAKS SGSALTVWGT GNPRRQFIYS LDLAQLFIWV LREYNEVEPI ILSVGEEDEV SIKEAAEAVV EAMDFHGEVT FDTTKSDGQF KKTASNSKLR TYLPDFRFTP FKQAVKETCA WFTDNYEQAR K.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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TSTA3

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