Troponin I-C

Alternative Names: TNNI3, CMH7, RCM1, CMD2A, MGC116817, TNNC1, TNNC, TNC, CMD1Z, Troponin I cardiac muscle, Cardiac troponin I, cTnI, Troponin C slow skeletal and cardiac muscles, TN-C.

The Troponin Complex is a significant protein involved in the regulation of muscle contraction in both skeletal and cardiac muscles. It is composed of three subunits: Troponin I, Troponin T, and Troponin C. Each subunit contributes to the overall function of the Troponin Complex. For instance, Troponin I inhibits the ATP-ase activity of acto-myosin. It is worth noting that Troponin T and Troponin I have different forms in cardiac muscles compared to skeletal muscles. To study the Troponin Complex, its purified subunits rcTnI, rcTnC, and rcTnT are recombined in a controlled laboratory environment.

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  • Sku: PSB-pro-346-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Single Chain Cardiac Troponin I-C 2nd generation is a member of the cardiac troponin family, which plays a vital role in regulating cardiac muscle contraction. This protein, with a weight of approximately X kilodaltons, is a synthetic version engineered through recombinant DNA technology. It serves as a sensitive biomarker for diagnosing myocardial infarction and assessing cardiac injury. Its precise and quantitative measurement aids in the timely identification of cardiac diseases, enabling effective treatment strategies. As a second-generation variant, this recombinant single chain cardiac troponin I-C offers improved sensitivity and specificity, making it a valuable tool in clinical settings for accurate cardiac assessment.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 91.0 % by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 30 kDa
Structure Heteromer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The protein solution contains 20mM Tris-HCl, 250mM NaCl and 50% glycerol, pH 7.5.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
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References

Not Available
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Troponin I-C
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