Troponin-C2

Alternative Names: Troponin C, TNNC2, skeletal muscle.

Troponin-C2 is a key regulatory antigen in controlling muscle contraction. It influences the activation of muscle fibers by calcium ions. Troponin-C2 consists of three subunits: Troponin I (Tn-I), Troponin T (Tn-T), and Troponin C (Tn-C). Tn-I inhibits actomyosin ATPase, Tn-T binds tropomyosin and Tn-C, and Tn-C binds calcium to counteract the inhibitory effects of the troponin complex on actin filaments. Any mutations in these components can lead to skeletal muscle disease.

Skip to product information
  • Sku: PSB-pro-2572-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
 per 
Shipping calculated at checkout.

Contact us directly for international purchases.

Title

Product Details

Product Description

Recombinant Human Troponin-C2 is a protein that belongs to the troponin family, specifically the troponin C subfamily. With a molecular weight of approximately 18.5 kDa, this protein plays a significant role in regulating muscle contraction by binding to calcium ions. Recombinant Human Troponin-C2 is produced through genetic engineering techniques, ensuring its purity and consistency for various research and diagnostic applications. Its precise and controlled calcium binding properties make it a valuable tool for studying the intricate mechanisms underlying muscle function and related disorders.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
18.1 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The protein (1mg/ml) contains 20 mM Tris-HCl buffer (pH 7.5), 1mM DTT, 100mM NaCl and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MTDQQAEARS YLSEEMIAEF KAAFDMFDAD GGGDISVKEL GTVMRMLGQT PTKEELDAII EEVDEDGSGT IDFEEFLVMM VRQMKEDAKG KSEEELAECF RIFDRNADGY IDPEELAEIF RASGEHVTDE EIESLMKDGD KNNDGRIDFD EFLKMMEGVQ.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

View full details

Troponin-C2

SUBHEADING

Recently viewed products