TNNI3 Native

Alternative Names: Cardiac troponin I, TNNI3, TNNC1, CMH7, RCM1, cTnI, CMD2A, MGC116817, Troponin I cardiac muscle.

Human Cardiac Troponin-I is a protein that plays a vital role in regulating cardiac muscle contraction. Belonging to the troponin family, it is specifically found in the heart muscle. With a molecular weight of approximately 23.5 kilodaltons, this protein is involved in the regulation of calcium-mediated muscle contraction. It acts as an inhibitory subunit, preventing the interaction between actin and myosin filaments until calcium binds to the troponin complex, initiating muscle contraction. Understanding the characteristics and functions of Human Cardiac Troponin-I is crucial for diagnosing and monitoring various cardiac conditions.

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  • Sku: PSB-pro-2788-10µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Human Cardiac Troponin-I is a protein that plays a vital role in regulating cardiac muscle contraction. Belonging to the troponin family, it is specifically found in the heart muscle. With a molecular weight of approximately 23.5 kilodaltons, this protein is involved in the regulation of calcium-mediated muscle contraction. It acts as an inhibitory subunit, preventing the interaction between actin and myosin filaments until calcium binds to the troponin complex, initiating muscle contraction. Understanding the characteristics and functions of Human Cardiac Troponin-I is crucial for diagnosing and monitoring various cardiac conditions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Human Cardiac Tissue
Purity 98.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation TNNI3 was lyophilized from 0.01M HCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Lyophilized Cardiac Troponin-I although stable at room temperature for 3 weeks, should be stored desiccated below -18° C. Upon reconstitution TNNI3 should be stored at 4° C between 2-7 days and for future use below -18° C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized TNNI3 in Tris/urea buffer (20mM Tris, pH 7.5, 7M urea, 5mM EDTA, 15mM 2-mercaptoethanol) not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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TNNI3 Native

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