TECK

Alternative Names: Thymus-expressed chemokine, C-C motif chemokine 25, Small-inducible cytokine A25, Chemokine TECK, CCL25, SCYA25, TECK, Ckb15, MGC150327.

CCL25 (Teck) is a unique CC chemokine with distant relation to other CC chemokines. It shares limited amino acid sequence identity with other chemokines. CCL25 is expressed primarily in the thymus and small intestine in humans and mice. Dendritic cells in the thymus are the main source of CCL25 production. CCL25 signals through the CCR9 receptor and may play a role in T-cell development. Recombinant human and mouse Teck have demonstrated chemotactic activity for activated macrophages, dendritic cells, and thymocytes. They are inactive on peripheral blood lymphocytes and neutrophils.

  •
  • Sku: PSB-chm-364-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Thymus Expressed Chemokine (CCL25) is a chemokine protein that belongs to the CC chemokine family. It plays a role in immune response by regulating the migration and activation of immune cells. CCL25 has a molecular weight of approximately 8.5 kDa. This protein is commonly used in research and therapeutic applications for its ability to modulate immune cell trafficking and inflammation.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
 Determined by its ability to chemoattract human monocytes using a concentration range of 1-10ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg. Determined by its ability to chemoattract human monocytes using a concentration range of 1-10ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 14.2 kDa
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Filtered (0.2µm) and lyophilized from a concentrated (1mg/ml) solution in 20mM PB, pH 7.4, 150mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNPKSREV QRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK LSSSKFSNPI SSSRKNVSLL ISANSGL.

Storage Instruction

Lyophilized TECK although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TECK should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized TECK in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
View full details

TECK
SUBHEADING

Recently viewed products