TARC His

Alternative Names: ABCD-2, A-152E5.3, CCL-17, CCL17, CC chemokine TARC, C-C motif chemokine 17, Small-inducible cytokine A17, SCYA17, Thymus and activation-regulated chemokine, TARC, MGC138271, MGC138273.

The TARC cDNA encodes a 94 amino acid precursor protein, with a 23 amino acid signal peptide cleaved off to yield the 71 amino acid mature secreted protein. TARC, a member of the CC chemokine family, shares amino acid sequence identity with several other chemokines. TARC is primarily expressed in the thymus, with lower levels in the lung, colon, and small intestine, and is temporarily expressed in stimulated peripheral blood mononuclear cells. Recombinant TARC is chemotactic for T cell lines but not monocytes or neutrophils. CCL-17, a ligand for the CCR4 receptor on T cells, is clustered among other Cys-Cys cytokine genes on chromosome 16q. It attracts T lymphocytes but not monocytes or granulocytes, and binds to chemokine receptors CCR4 and CCR8. CCL17 plays important roles in T cell development and activation.

  •
  • Sku: PSB-chm-359-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Thymus and Activation Regulated Chemokine (CCL17) His Tag is a protein belonging to the chemokine family. It plays a role in immune response regulation and cell migration. With a molecular weight of approximately 8.4 kDa, this protein is commonly used in research settings to study its effects on immune cell function. The addition of the His Tag allows for easy purification and detection of the protein in experimental assays.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The TARC protein contains 1xPBS (pH7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MARGTNVGRE CCLEYFKGAI PLRKLKTWYQ TSEDCSRDAI VFVTVQGRAI CSDPNNKRVK NAVKYLQSLE RS.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
View full details

TARC His
SUBHEADING

Recently viewed products