Streptokinase

Alternative Names: SK, Streptokinase.

Streptokinase, an extracellular enzyme produced by beta-haemolytic streptococcus, is used for clot dissolution in myocardial infarction and pulmonary embolism treatment. As a metallo-enzyme, it falls under the category of fibrinolytics and functions by cleaving plasminogen to generate plasmin. This cost-effective medication has proven efficacy in certain cases.

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  • Sku: PSB-enz-315-250,000IU
  • Vendor: ProSpec-Tany
$210.00 USD
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Title

Product Details

Product Description

Recombinant Streptokinase is a biotechnologically engineered protein that belongs to the serine protease family. With a weight of approximately 47 kDa, it is widely utilized in the field of medicine for its fibrinolytic properties. This enzyme effectively dissolves blood clots by activating plasminogen, thereby promoting the breakdown of fibrin. Recombinant Streptokinase plays a significant role in thrombolytic therapy, aiding in the treatment of conditions such as myocardial infarction and pulmonary embolism. Its precise mechanism of action and therapeutic potential make it a valuable tool in the management of clot-related disorders.

Current Lead Time

7-14 Days

Product Specifications

Species
bacteria
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
The specific biological activity measured by the ability of fibrin lysis in agarose plate was found to be 80000IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation Lyophilized from a 0.2µm filtered concentrated (1mg/ml) solution in PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

IAGPEWLLDR PSVNNSQLVV SVAGTVEGTN QDISLKFFEI DLTSRPAHGG KTEQGLSPKS KLFATDSGAM PHKLEKADLL KAIQEQLIAN VHSNDDYFEV IDFASDATIT DRNGKVYFAD KDGSVTLPIQ PVQEFLLKGH VRVRPYKEKP VQNQAKSVDV EYTVQFTPLN PDDDFRPALK DTKLLKTLAI GDTITSQELL AQAQSILNKN HPGYTIYERD SSIVTHDNDI FRTILPMDQE FTYHVKNREQ AYRINKKSGL NEEINNTDLI SEKYYVLKKG EKPYDPFDRS HLKLFTIKYV DVNTNELLKS EQLLTASERN LDFRDLYDPR DKAKLLYNNL DAFGIMDYTL TGKVEDNHDD TNRIITVYMG KRPEGENASY HLAYDKDRYT EEEREVYSYL RYTGTPIPDN PNDK.

Storage Instruction

Lyophilized Streptokinase although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Streptokinase should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Streptokinase in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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Streptokinase

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