Sincalide

Alternative Names: Not Available

Sincalide, the C-terminal octapeptide of cholecystokinin (CCK), causes contraction of the gallbladder wall by acting on its receptors. CCK is a hormone originally isolated from porcine intestinal mucosa. It is a 33-amino acid peptide that contains a sulfated tyrosine, which is crucial for its biological activity. CCK is found in mammals in both the digestive tract and the central nervous system. In addition to its various biological functions, CCK stimulates pancreatic exocrine secretion, gallbladder contraction, and intestine motility. It may also have neurotransmitter/neuromodulator effects in the central nervous system.

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  • Sku: PSB-hor-274-1mg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Sincalide, a synthetic peptide, is a medication used in medical procedures to stimulate gallbladder contraction and pancreatic secretion. Belonging to the cholecystokinin family, this pharmaceutical compound has a molecular weight of approximately 1635.9 Daltons. Sincalide acts by binding to specific receptors in the gastrointestinal tract, triggering the release of digestive enzymes and promoting the emptying of bile from the gallbladder. Its precise mechanism of action and clinical applications make Sincalide a noteworthy substance in the field of gastroenterology and diagnostic imaging.

Current Lead Time

7-14 Days

Product Specifications

Species
Contact for Details
Expression System Contact for Details
Purity 99.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The Sincalide was lyophilized from a concentrated (1mg/ml) solution with no additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Lyophilized Sincalide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCK-8 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Sincalide in sterile 18MΩ-cm H2O at a concentration of 0.5mg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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Sincalide

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