SCGB2A2 HEK

Alternative Names: Mammaglobin-A, Mammaglobin-1, Secretoglobin family 2A member 2, SCGB2A2, MGB1, UGB2, MGC71974. Reordered series: Mammaglobin-A, Mammaglobin-1, Secretoglobin family 2A member 2, SCGB2A2, MGB1, UGB2, MGC71974.

The mammaglobin gene was discovered through a screening method aimed at finding new genes associated with human breast cancer. Mammaglobin produces a 10 kDa glycoprotein and is distantly related to other epithelial secretory proteins such as rat estramustine-binding protein/prostatein and human Clara cell 10 kDa protein (CC10)/uteroglobin. Mammaglobin, a specific member of the uterglobin family that is found in mammary tissue, is known to be overexpressed in human breast cancer. Studies suggest that mammaglobin is a relatively sensitive and specific marker (85%) for breast cancer. It could be used alongside BRST-2 (GCDFP-15) and ER to evaluate tumors where the site of origin is unknown. The mammaglobin gene (SCGB2A2) is located on chromosome 11 at the 11q13 locus. SCGB2A2 belongs to the secretoglobin superfamily, which consists of small secreted proteins that can form dimers and sometimes have sugar molecules attached to them. These secretoglobins are mainly found in mucosal tissue and are involved in cell signaling, immune response, chemotaxis, and potentially act as transporters for steroid hormones in humans.

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  • Sku: PSB-pro-2038-2µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Mammaglobin-A, HEK is a protein belonging to the mammaglobin family. With a molecular weight of [insert weight], this protein plays a significant role in various biological processes. Mammaglobin-A is predominantly expressed in breast tissue and has been extensively studied for its potential as a biomarker in breast cancer detection and diagnosis. The recombinant form of this protein, produced using human embryonic kidney (HEK) cells, offers a reliable and consistent source for research and diagnostic applications.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System HEK 293
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation SCGB2A2 was filtered (0,4µm) and lyophilized from 0.5mg/ml in PBS buffer and 5% (w/v) ThrealosepH 7.4

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

GSGCPLLENV ISKTINPQVS KTEYKELLQE FIDDNATTNA IDELKECFLN QTDETLSNVE VFMQLIYDSS LCDLF KLENL YFQGPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H.

Storage Instruction

Store lyophilized protein at -20° C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4° C for 5 days.

Sample Prep Instruction

It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture.

References

Not Available
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SCGB2A2 HEK
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