SAMSN1

Alternative Names: NASH1, Nash1, SAMSN1, HACS1, SASH2, SLy2, SH3D6B, SAM domain-containing protein SAMSN-1, Hematopoietic adaptor containing SH3 and SAM domains 1, SAM domain, SH3 domain and nuclear localization signals protein 1, SH3-SAM adaptor protein.

SAMSN1, a member of adaptors and scaffold proteins with SH3 and SAM domains, serves as a negative regulator of B-cell activation and inhibits cell proliferation. It is up-regulated by IL-4 in activated B cells and primarily expressed in dendritic cells. SAMSN1 shares a similar function with other adaptor proteins in connecting signaling molecules in signal transduction cascades.

  •
  • Sku: PSB-pro-1995-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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UniProt Listing
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Product Details

Product Description

Recombinant Human SAM Domain SH3 Domain and Nuclear Localization Signal 1 is a protein belonging to the SAM domain-containing protein family. This protein plays a significant role in various cellular processes, including protein-protein interactions and signal transduction. With a weight of approximately [insert weight], it exhibits a crucial function in mediating the localization of proteins to the cell nucleus. This recombinant protein holds immense potential for studying cellular mechanisms and developing therapeutic interventions, making it a valuable tool in scientific research.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 80.0% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 44.1 kDa
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation SAMSN1 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 30% glycerol 0.1M NaCl and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMLKRKPS NVSEKEKHQK PKRSSSFGNF DRFRNNSLSK PDDSTEAHEG DPTNGSGEQS KTSNNGGGLG KKMRAISWTM KKKVGKKYIK ALSEEKDEED GENAHPYRNS DPVIGTHTEK VSLKASDSMD SLYSGQSSSS GITSCSDGTS NRDSFRLDDD GPYSGPFCGR ARVHTDFTPS PYDTDSLKIK KGDIIDIICK TPMGMWTGML NNKVGNFKFI YVDVISEEEA APKKIKANRR SNSKKSKTLQ EFLERIHLQE YTSTLLLNGY ETLEDLKDIK ESHLIELNIE NPDDRRRLLS AAENFLEEEI IQEQENEPEP LSLSSDISLN KSQLDDCPRD SGCYISSGNS DNGKEDLESE NLSDMVHKII ITEPSD.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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SAMSN1
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