S100A4

Alternative Names: S100 calcium-binding protein A4, Protein S100-A4, Metastasin, Protein Mts1, Placental calcium-binding protein, Calvasculin, S100A4, CAPL, MTS1, 42A, 18A2, FSP1, P9KA, PEL98.

S100A4 is a protein belonging to the S100 super-family, which includes proteins with 2 EF-hand calcium binding domains. It is commonly overexpressed and found in the cytoplasm or nucleus. S100A4 plays a role in motility, invasion, and tubulin polymerization. Abnormalities in the S100A4 gene, such as chromosomal rearrangements and altered expression, have been linked to tumor metastasis.

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  • Sku: PSB-pro-698-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human S100 Calcium Binding Protein A4, also known as S100A4, is a member of the S100 protein family. This protein is involved in various cellular processes, including cell motility, invasion, and metastasis. With a molecular weight of approximately 11.4 kDa, S100A4 plays a significant role in the regulation of cytoskeleton dynamics and the promotion of tumor progression. Its calcium-binding properties enable it to interact with target proteins, leading to the modulation of cell signaling pathways. This recombinant protein holds potential in research areas such as cancer biology and tissue regeneration.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation S100A4 protein at in 20mM Tris-HCl, pH-8 & 10% Glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MACPLEKALD VMVSTFHKYS GKEGDKFKLN KSELKELLTR ELPSFLGKRT DEAAFQKLMS NLDSNRDNEVDFQEYCVFLS CIAMMCNEFF EGFPDKQPRK K.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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S100A4
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