S100A13

Alternative Names: Protein BEX1, Brain-expressed X-linked protein 1, BEX2, HBEX2, HGR74-h

Brain Expressed X-Linked 1 (BEX1) is a signaling adapter molecule that plays a role in cell cycle progression and neuronal differentiation. It is involved in p75NTR/NGFR signaling and inhibits neuronal differentiation when exposed to nerve growth factor. BEX1 acts as an upstream modulator of receptor signaling, connecting the cell cycle and neurotrophic factor signaling. This allows for the adjustment of biological responses to external signals based on the internal cellular states.

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  • Sku: PSB-pro-153-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human S100 Calcium Binding Protein A13, also known as S100A13, is a member of the S100 protein family. This protein plays a significant role in various cellular processes, including cell growth, differentiation, and migration. With a molecular weight of approximately 10.5 kDa, it acts as a calcium sensor and modulator of intracellular calcium levels. S100A13 is involved in the regulation of protein-protein interactions and has been implicated in several pathological conditions, such as cancer progression and metastasis. Its precise functions and mechanisms are still under investigation, making it a subject of interest in biomedical research.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 80% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
17.2 kDa
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The BEX1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 30% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMESKEKR AVNSLSMENA NQENEEKEQV ANKGEPLALP LDAGEYCVPR GNRRRFRVRQ PILQYRWDMM HRLGEPQARM REENMERIGE EVRQLMEKLR EKQLSHSLRA VSTDPPHHDH HDEFCLMP.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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S100A13

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