S100A1

Alternative Names: S100, S100A, S100A1, S100-alpha, S100 calcium-binding protein A1, S-100 protein alpha subunit, S-100 protein alpha chain, Protein S100-A1, S100-A1.

S100A1 is a type of calcium-binding protein within the S100 family. It plays a role in activating the release of calcium in the sarcoplasm and regulating the polymerization of intermediate filaments. S100A1 may also stimulate the release of calcium triggered by calcium, inhibit the formation of microtubules, and hinder the phosphorylation process mediated by protein kinase C. When there is a decrease in the expression of S100A1, it has been linked to cardiomyopathies. S100 proteins can be found in either the cytoplasm or nucleus of various cells. The S100 gene family consists of at least 13 members that are clustered together on chromosome 1q21.

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  • Sku: PSB-pro-364-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human S100 Calcium Binding Protein A1, also known as S100A1, is a member of the S100 protein family. This protein is involved in calcium-dependent regulation of various cellular processes, including cell growth, differentiation, and apoptosis. With a molecular weight of approximately 10.5 kilodaltons, S100A1 plays a role in the regulation of intracellular calcium levels and is predominantly expressed in cardiac and skeletal muscle tissues. Understanding the functions and characteristics of Recombinant Human S100 Calcium Binding Protein A1 contributes to the broader understanding of calcium signaling and its implications in various physiological processes.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The S100A1 protein was lyophilized from 0.4µm filtered solution at a concentration of 0.5mg/ml containing 20mM Tris pH-7.5 and 50mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MKHHHHHHAS GSELETAMET LINVFHAHSG KEGDKYKLSK KELKELLQTE LSGFLDAQKD VDAVDKVMKE LDENGDGEVD FQEYVVLVAA LTVACNNFFW ENS.

Storage Instruction

Lyophilized S100A1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution S100A1 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

Add deionized water to a working concentration approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by appropriate sterile filter before using it in the cell culture.

References

Not Available

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S100A1

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