RTN4R

Alternative Names: Not Available

Recombinant Human Reticulon 4 Receptor, also known as RTN4R, is a transmembrane protein that plays a significant role in regulating neuronal growth and development. Belonging to the reticulon family, this receptor is involved in mediating axonal regeneration and plasticity. With a molecular weight of approximately X kDa, RTN4R interacts with various ligands and signaling pathways to modulate neuronal connectivity and synaptic plasticity. Understanding the functional properties and mechanisms of RTN4R can provide valuable insights into neurodevelopmental disorders and potential therapeutic interventions.

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  • Sku: PSB-pro-2353-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Reticulon 4 Receptor, also known as RTN4R, is a transmembrane protein that plays a significant role in regulating neuronal growth and development. Belonging to the reticulon family, this receptor is involved in mediating axonal regeneration and plasticity. With a molecular weight of approximately X kDa, RTN4R interacts with various ligands and signaling pathways to modulate neuronal connectivity and synaptic plasticity. Understanding the functional properties and mechanisms of RTN4R can provide valuable insights into neurodevelopmental disorders and potential therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Sf9 - Baculovirus cells
Purity 90% by SDS-PAGE
Activity
Activity Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
46.3 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation RTN4R protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

CPGACVCYNE PKVTTSCPQQ GLQAVPVGIP AASQRIFLHG NRISHVPAAS FRACRNLTIL WLHSNVLARI DAAAFTGLAL LEQLDLSDNA QLRSVDPATF HGLGRLHTLH LDRCGLQELG PGLFRGLAAL QYLYLQDNAL QALPDDTFRD LGNLTHLFLH GNRISSVPER AFRGLHSLDR LLLHQNRVAH VHPHAFRDLG RLMTLYLFAN NLSALPTEAL APLRALQYLR LNDNPWVCDC RARPLWAWLQ KFRGSSSEVP CSLPQRLAGR DLKRLAANDL QGCAVATGPY HPIWTGRATD EEPLGLPKCC QPDAADKASV LEPGRPASAG NALKGRVPPG DSPPGNGSGP RHINDSPFGT LPGSAEPPLT AVRPEGSEPP GFPTSGPRRR PGCSRKNRTR SHCRLGQAGS GGGGTGDSEG SLEHHHHHH.

Storage Instruction

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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RTN4R

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