RSG1

Alternative Names: C1orf89, REM2- and Rab-like small GTPase 1, RSG1, RP4-733M16.4.

REM2 and RSG1 are involved in targeted membrane trafficking, particularly in the fusion of vesicles with membranes. RSG1 plays a crucial role in cilium biogenesis by controlling the transport of cargo proteins to the basal body and the apical tips of cilia. Additionally, RSG1 serves as a potential effector in the planar cell polarity signaling pathway and is implicated in exocytosis in secretory cells.

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  • Sku: PSB-pro-1334-1µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human REM2 and RAB-Like Small GTPase 1 is a protein that belongs to the RAS superfamily of small GTPases. This protein plays a significant role in various cellular processes, including intracellular vesicle trafficking, signal transduction, and cytoskeletal organization. With a molecular weight of approximately X kDa, it functions as a molecular switch by cycling between an active GTP-bound state and an inactive GDP-bound state. Understanding the intricate mechanisms and functions of this protein is crucial for gaining insights into cellular physiology and potentially developing therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
30.9 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation RSG1 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.5), 0.2M NaCl, 50% glycerol and 2mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMARPPVP GSVVVPNWHE SAEGKEYLAC ILRKNRRRVF GLLERPVLLP PVSIDTASYK IFVSGKSGVG KTALVAKLAG LEVPVVHHET TGIQTTVVFW PAKLQASSRV VMFRFEFWDC GESALKKFDH MLLACMENTD AFLFLFSFTD RASFEDLPGQ LARIAGEAPG VVRMVIGSKF DQYMHTDVPE RDLTAFRQAW ELPLLRVKSV PGRRLADGRT LDGRAGLADV AHILNGLAEQ LWHQDQVAAG LLPNPPESAP E.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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RSG1

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