rSCGB1A1

Alternative Names: Uteroglobin, Ugb, Utg, UG, Clara cell 17 kDa protein, CC10, Clara cells 10 kDa secretory protein, CCPBP, Clara cell phospholipid-binding protein, PCB-binding protein, PCB-BP, Clara cell phospholipid-binding protein, Secretoglobin family 1A member 1, Scgb1a1, Clara cell 16 kDa protein, CCSP, CC16.

Uteroglobin is a multifunctional protein belonging to the Secretoglobin superfamily that has anti-inflammatory and anti-tumorigenic properties. It binds small hydrophobic molecules such as phospholipids and prostaglandins, inhibits phospholipase A2, and sequesters hydrophobic ligands. Expressed by Clara cells in the lungs and other epithelial cells, Uteroglobin plays a role in sequestering pro-inflammatory mediators and carcinogens, inhibiting cell migration and invasion, platelet aggregation, and T cell differentiation. Defects in the SCGB1A1 gene are linked to a susceptibility to asthma.

  •
  • Sku: PSB-cyt-820-10µg
  • Vendor: ProSpec-Tany
$60.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Rat Uteroglobin is a protein belonging to the secretoglobin family, known for its anti-inflammatory properties. With a molecular weight of approximately 18 kDa, this protein plays a role in regulating immune responses and protecting against oxidative stress. Recombinant Rat Uteroglobin is commonly used in research studies to investigate its potential therapeutic applications in various inflammatory conditions.

Current Lead Time

7-14 Days

Product Specifications

Species
 Rat
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
 Fully biologically active when compared to standard. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 ?g/ml, corresponding to a specific activity of >200IU/mg. Fully biologically active when compared to standard. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 ?g/ml, corresponding to a specific activity of >200IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 17.0 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation SCGB1A1 protein was lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

SSDICPGFLQ VLEALLLGSE SNYEAALKPF NPASDLQNAG TQLKRLVDTL PQETRINIVK LTEKILTSPL CEQDLRV

Storage Instruction

Lyophilized SCGB1A1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution SCGB1A1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Sample Prep Instruction

It is recommended to reconstitute the lyophilized SCGB1A1 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
View full details

rSCGB1A1
SUBHEADING

Recently viewed products