rRantes

Alternative Names: Small inducible cytokine A5, SCYA5, chemokine (C-C motif) ligand 5, CCL5, T-cell-specific RANTES protein, RANTES, T cell- specific protein P228, TCP228, T-cell-specific protein P228, D17S136E, MGC17164, SIS-delta, SISd.

RANTES, also known as CCL5, is an 8 kDa chemotactic cytokine that attracts T cells, eosinophils, and basophils to sites of inflammation. It plays a role in recruiting leukocytes and activating NK cells with the help of specific cytokines, such as IL-2 and IFN-?. RANTES is also a HIV-suppressive factor released by CD8+ T cells and is located on chromosome 17 in humans.

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  • Sku: PSB-chm-352-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Rat Rantes (CCL5) is a chemokine protein that belongs to the CC chemokine family. It plays a key role in immune responses by regulating the migration and activation of various immune cells. This protein has a molecular weight of approximately 8.6 kDa. Recombinant Rat Rantes is commonly used in research studies to investigate its role in inflammation, autoimmune diseases, and cancer progression.

Current Lead Time

7-14 Days

Product Specifications

Species
 Rat
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 The activity is determined by the ability to chemoattract total human lymphocytes and murine T-cells at a concentration between 1-10ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg. The activity is determined by the ability to chemoattract total human lymphocytes and murine T-cells at a concentration between 1-10ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Lyophilized from a concentrated (1mg/ml) solution in water containing no additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS.

Storage Instruction

Lyophilized Rat Rantes although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Rat CCL5 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Rantes in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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