RND1

Alternative Names: GTP-binding protein, ras homolog gene family, member S, Rho family GTPase 1, rho-related GTP-binding protein Rho6, RHO6, Rnd1, ARHS, RHOS, FLJ42294.

RND1 is a distinct member of the Rho family due to its unique characteristics in charge, size, and biochemical properties. It primarily exists in the activated GTP-bound form and acts as a negative regulator of actin assembly and cell adhesion. Additionally, RND1 plays a role in organizing the actin cytoskeleton in response to external growth factors.

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  • Sku: PSB-pro-893-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Rho Family GTPase 1 is a protein that belongs to the Rho family of GTPases, which are crucial regulators of cellular processes such as cytoskeletal dynamics, cell motility, and gene expression. With a molecular weight of approximately X kDa, this protein plays a significant role in signal transduction pathways by cycling between an inactive GDP-bound state and an active GTP-bound state. Its precise function varies depending on the specific cellular context, but it is involved in diverse cellular processes, including cell migration, adhesion, and proliferation. Understanding the molecular mechanisms and functions of Recombinant Human Rho Family GTPase 1 contributes to the broader understanding of cellular physiology and disease progression.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The RND1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 0.1M NaCl and 30% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MKERRAPQPV VARCKLVLVG DVQCGKTAML QVLAKDCYPE TYVPTVFENY TACLETEEQR VELSLWDTSG SPYYDNVRPL CYSDSDAVLL CFDISRPETV DSALKKWRTE ILDYCPSTRV LLIGCKTDLR TDLSTLMELS HQKQAPISYE QGCAIAKQLG AEIYLEGSAF TSEKSIHSIF RTASMLCLNK PSPLPQKSPV

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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RND1

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