rmTARC

Alternative Names: ABCD-2, A-152E5.3, C-C motif chemokine 17, CC chemokine TARC, CCL-17, CCL17, MGC138271, MGC138273, SCYA17, Small-inducible cytokine A17, Thymus and activation-regulated chemokine, TARC.

The TARC gene encodes a protein with a 23 amino acid signal peptide that is cleaved to form a 71 amino acid mature protein. TARC shows similarities with other chemokines like RANTES and MIP-1a. It is mainly expressed in the thymus and to a lesser extent in the lung, colon, and small intestine, as well as in stimulated peripheral blood mononuclear cells. TARC is chemotactic for T cell lines but not monocytes or neutrophils. CCL-17, a ligand for CCR4, is part of the CC cytokine gene cluster on chromosome 16 and is implicated in T cell development and activation.

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  • Sku: PSB-chm-036-50µg
  • Vendor: ProSpec-Tany
$400.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Rhesus Macaque Thymus and Activation Regulated Chemokine (CCL17) is a protein belonging to the chemokine family. This chemokine is involved in the regulation of immune cell migration and activation. With a molecular weight of approximately 8.5 kDa, CCL17 plays a role in inflammatory responses and allergic reactions. Researchers utilize recombinant CCL17 in studies related to immunology and inflammation to better understand its functions and potential therapeutic applications.

Current Lead Time

7-14 Days

Product Specifications

Species
 Macaque
Expression System E. coli
Purity 97.0 % by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, 0.02 % Tween-20 and 300mM NaCl, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ARGTNVGREC CLKYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQNKAIC SDPNDKKVKK ALKYLQSLER S.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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rmTARC
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