rmRantes

Alternative Names: Small inducible cytokine A5, SCYA5, chemokine (C-C motif) ligand 5, CCL5, T-cell-specific RANTES protein, RANTES, T cell- specific protein P228, TCP228, T-cell-specific RANTES protein, SIS-delta, SISd, D17S136E, MGC17164.

RANTES, also known as CCL5, is an 8 kDa chemotactic cytokine that attracts T cells, eosinophils, and basophils to inflammatory sites. Alongside certain cytokines like IL-2 and IFN-?, RANTES helps stimulate the growth and activation of NK cells to form CHAK cells. Additionally, RANTES is a factor that suppresses HIV and is produced by CD8+ T cells. Its gene is located on chromosome 17 in humans.

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  • Sku: PSB-chm-342-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Mouse Rantes (CCL5) is a chemokine protein belonging to the CC chemokine family. It plays a role in immune response and inflammation by attracting immune cells to sites of infection or injury. With a molecular weight of approximately 8.8 kDa, Recombinant Mouse Rantes is commonly used in research to study chemotaxis and immune cell recruitment mechanisms. Its ability to modulate immune cell migration makes it a valuable tool for investigating inflammatory diseases and developing potential therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Mouse
Expression System E. coli
Purity 95.0 % by SDS-PAGE
Activity
The activity is determined by the ability to chemoattract total human lymphocytes and murine T-cells at a concentration between 1-10ng/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation Lyophilized from a concentrated (1mg/ml) solution in water containing no additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS.

Storage Instruction

Lyophilized Mouse Rantes although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Mouse CCL5 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Rantes in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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rmRantes

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