rmIL6

Alternative Names: IFN-b2, IFN beta-2, B cell differentiation factor, BCDF, BSF-2, B-cell stimulatory factor 2, HPGF, HSF, MGI-2, Hybridoma growth factor, CTL differentiation factor, CDF, IL-6, HGF.

Il-6 is a versatile cytokine that exhibits various biological functions. It is crucial for the final differentiation of b-cells into ig-secreting cells, promotes the growth of myeloma and plasmacytoma, stimulates nerve cell differentiation, and triggers the production of acute phase reactants in hepatocytes.

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  • Sku: PSB-cyt-174-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Rhesus Macaque Interleukin-6 is a protein that plays a significant role in immune response regulation and inflammation. Belonging to the cytokine family, it acts as a mediator in various biological processes. With a weight of approximately 22.7 kDa, Recombinant Rhesus Macaque Interleukin-6 is involved in cell signaling pathways and is crucial for maintaining homeostasis within the immune system. Its precise functions and interactions make it a subject of scientific interest for understanding immune-related diseases and developing potential therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Macaque
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using IL-6-dependent murine 7TD1 cells is less than 0.1ng/ml, corresponding to a specific activity of > 1.0 × 10,000,000 IU/mg. Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using IL-6-dependent murine 7TD1 cells is less than 0.1ng/ml, corresponding to a specific activity of > 1.0 × 10,000,000 IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
21.1 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MAPVLPGEDS KNVAAPHSQP LTSSERIDKH IRYILDGISA LRKETCNRSN MCESSKEALA ENNLNLPKMA EKDGCFQSGF NEDTCLVKII TGLLEFEVYL EYLQNRFESS EEQARAVQMS TKVLIQFLQK KAKNLDAITT PEPTTNASLL TKLQAQNQWL QDMTTHLILR SFKEFLQSNL RALRQM

Storage Instruction

Lyophilized IL-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL-6 should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized ;IL-6 in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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rmIL6

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