rmFlt3 Ligand

Alternative Names: Fms-related tyrosine kinase 3 ligand, FLK2, STK1, CD135, Stem Cell Tyrosine Kinase 1, FLT3LG, Flt3.

FLT3 ligand is a receptor with tyrosine-protein kinase activity and acts as a growth factor in regulating the proliferation of early hematopoietic cells. It works together with other CSFs and interleukins to induce both cell growth and differentiation.

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  • Sku: PSB-cyt-157-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Rhesus Macaque Flt3-Ligand is a protein that belongs to the cytokine family. With a weight of approximately X kDa, it plays a significant role in the regulation of hematopoiesis and immune cell development. This protein is involved in the differentiation and proliferation of various cell types, including dendritic cells and hematopoietic stem cells. By binding to its receptor, Flt3, it activates downstream signaling pathways, ultimately leading to the expansion and maturation of these cell populations. The recombinant form of Rhesus Macaque Flt3-Ligand has been extensively studied for its potential applications in immunotherapy and vaccine development.

Current Lead Time

7-14 Days

Product Specifications

Species
Macaque
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
The ED50 as calculated by the dose-dependant stimulation of the proliferation of human AML5 cells is less than 1.0ng/ml, corresponding to a specific activity of 1,000,000IU/mg. The ED50 as calculated by the dose-dependant stimulation of the proliferation of human AML5 cells is less than 1.0ng/ml, corresponding to a specific activity of 1,000,000IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
18.0 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVPSNLQD EELCGALWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQHP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPRSPGALEA TALTAPQRP

Storage Instruction

Lyophilized Flt3 Ligand Rhesus Macaque although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Flt3 Ligand Rhesus Macaque should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Flt3 Ligand in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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rmFlt3 Ligand

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