rmEotaxin

Alternative Names: Small inducible cytokine A11, SCYA11, CCL11, Eosinophil chemotactic protein, chemokine (C-C motif) ligand 11, MGC22554.

CCL11, also known as eotaxin, belongs to the CC chemokine family and plays a role in recruiting eosinophils during allergic responses. Its effects are mediated through binding to specific chemokine receptors, including CCR2, CCR3, and CCR5. The gene for human CCL11 (scya11) is located on chromosome 17 and consists of three exons.

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  • Sku: PSB-chm-022-5µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Rhesus Macaque Eotaxin (CCL11) is a chemokine protein belonging to the CC chemokine family. This protein plays a role in the recruitment of eosinophils to sites of inflammation. With a molecular weight of approximately 8.6 kDa, Recombinant Rhesus Macaque Eotaxin (CCL11) is commonly used in research studies to investigate the mechanisms of allergic reactions and inflammatory responses in primates.

Current Lead Time

7-14 Days

Product Specifications

Species
 Macaque
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
 Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration range of 0.1-10.0 ng/ml corresponding to a specific activity of 1.0 × 105 - 1.0 × 107 IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation The Eotaxin was lyophilized from a 0.2µm filtered concentrated solution in 2×PBS, pH 7.0.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

GPDSVATTCC FTLTNKKIPL QRLESYRRII SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDRKSP TPKP

Storage Instruction

Lyophilized Eotaxin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Eotaxin should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Eotaxin Recombinant in sterile distilled H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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rmEotaxin
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