rmBCA1

Alternative Names: C-X-C motif chemokine 13, Small-inducible cytokine B13, B lymphocyte chemoattractant, CXC chemokine BLC, CXCL13, BCA1, BCA-1, CXCL-13, B cell Attracting Chemokine-1, BLC, ANGIE, BLR1L, SCYB13, ANGIE2

BCA-1 is a chemokine found in secondary lymphoid organs like the spleen, lymph nodes, and Peyer's patches. It plays a role in attracting B lymphocytes to follicles by interacting with the Burkitt's lymphoma receptor 1 (BLR1). Human BCA-1 has a 64% similarity in amino acid sequence with the mouse protein and 23 - 34% similarity with other CXC chemokines. BCA-1 is a strong attractant for B lymphocytes but not for T lymphocytes, monocytes or neutrophils. BLR1 (now known as CXCR-5) is the specific receptor for BCA1, mainly expressed in B lymphocytes and a subset of T helper memory cells.

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  • Sku: PSB-chm-035-50µg
  • Vendor: ProSpec-Tany
$400.00 USD
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Title

Product Details

Product Description

Recombinant Rhesus Macaque BCA-1/ BLC (CXCL13) is a chemokine protein belonging to the CXC subfamily. This protein plays a role in the recruitment of B cells to lymphoid tissues. With a molecular weight of approximately 8.2 kDa, Recombinant Rhesus Macaque BCA-1/ BLC (CXCL13) is a key player in the immune response, functioning as a chemoattractant for B cells. This protein is essential for the proper functioning of the immune system and is commonly used in research studies related to immunology and inflammation.

Current Lead Time

7-14 Days

Product Specifications

Species
Macaque
Expression System E. coli
Purity 95.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
10.3 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation Lyophilized from a 0.2μm filtered concentrated solution in 20mM Tris-HCl, pH 8.0 and 300mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

VLEVYYTHLR CRCVQESSVF IPRRFIDRIQ ISPRGNGCPR KEIIVWKKNK SVVCVDPQAE WIQRIMEMLR KKSSSTPPVP VFKRKIP.

Storage Instruction

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized BCA-1/ BLC (CXCL13) Rhesus Macaque in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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rmBCA1

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