rIP10

Alternative Names: C-X-C motif chemokine 10, Cxcl10, Gamma-IP10, IP-10, Inp10, Protein Mob-1, Mob1, Small-inducible cytokine B10, Scyb10.

Chemokine (C-X-C motif) ligand 10 (CXCL10) is a small cytokine in the CXC chemokine family. It is secreted by various cell types in response to IFN-?, such as monocytes, endothelial cells, and fibroblasts. CXCL10 plays multiple roles including attracting monocytes and T cells, promoting T cell adhesion to endothelial cells, and inhibiting tumor growth and bone marrow colony formation. The gene for CXCL10 is located on human chromosome 4 alongside other CXC chemokines. It exerts its effects by binding to the CXCR3 chemokine receptor. The three-dimensional crystal structure of CXCL10 has been analyzed under three different conditions with a high resolution of up to 1.92A.

  •
  • Sku: PSB-chm-264-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Rat IP-10 (CXCL10) is a chemokine belonging to the CXC family, known for its role in immune responses and inflammation. With a molecular weight of approximately 8.7 kDa, this protein is involved in the recruitment and activation of leukocytes at sites of infection or injury. Recombinant Rat IP-10 is commonly used in research settings to study its effects on immune cell migration and inflammatory processes.

Current Lead Time

7-14 Days

Product Specifications

Species
 Rat
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
 Determined by its ability to chemoattract hCXCR3/HEK293 cells using a concentration range of 10.0-50.0 ng/ml. Determined by its ability to chemoattract hCXCR3/HEK293 cells using a concentration range of 10.0-50.0 ng/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMKKNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP.

Storage Instruction

Lyophilized IP-10 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL10 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized IP-10 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
View full details

rIP10
SUBHEADING

Recently viewed products