RHOQ

Alternative Names: RHOQ, ARHQ, RASL7A, TC10, TC10A, Rho-related GTP-binding protein RhoQ, Ras-like protein TC10, Ras-like protein family member 7A.

RHOQ is a signaling G protein that can switch between an active state (GTP-bound) and an inactive state (GDP-bound). When active, RHOQ interacts with various effector proteins to regulate cellular responses. It belongs to the Rac subfamily of the Rho family of GTPases and is involved in epithelial cell polarization processes. Moreover, RHOQ also plays a part in CFTR trafficking to the plasma membrane. One of its effects is the creation of filopodia, which are thin surface projections rich in actin.

  •
  • Sku: PSB-pro-1451-2µg
  • Vendor: ProSpec-Tany
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UniProt Listing
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Product Details

Product Description

Recombinant Human Ras Homolog Gene Family Member Q, also known as RhoQ, is a protein belonging to the Ras superfamily, which plays a significant role in cellular signaling pathways. RhoQ is a small GTPase protein with a molecular weight of approximately 21 kDa. This protein is involved in regulating various cellular processes, including cytoskeletal organization, cell migration, and vesicle trafficking. Understanding the functional mechanisms of RhoQ can provide insights into its potential implications in disease development and therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 24.7 kDa
Structure Monomer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation RHOQ protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAHGPGA LMLKCVVVGD GAVGKTCLLM SYANDAFPEE YVPTVFDHYA VSVTVGGKQY LLGLYDTAGQ EDYDRLRPLS YPMTDVFLIC FSVVNPASFQ NVKEEWVPEL KEYAPNVPFL LIGTQIDLRD DPKTLARLND MKEKPICVEQ GQKLAKEIGA CCYVECSALT QKGLKTVFDE AIIAILTPKK HTVKKRIGSR CINCC.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
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References

Not Available
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RHOQ
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