RHOA

Alternative Names: RHOA, RhoA, ARH12, ARHA, Rho cDNA clone 12, RHO12, RHOH12, h12, Transforming protein RhoA.

RhoA, a member of the small GTPase superfamily, is involved in regulating cell division. It regulates the actin cytoskeleton and interacts with two proteins, ROCK1 and DIAPH1.

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  • Sku: PSB-pro-057-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Ras Homolog Gene Family Member A, also known as RHOA, is a protein belonging to the Ras superfamily of small GTPases. With a molecular weight of approximately 21 kilodaltons, RHOA plays a significant role in regulating various cellular processes, including cytoskeletal dynamics, cell migration, and cell adhesion. Its involvement in signal transduction pathways makes it an essential component in maintaining cellular homeostasis. Understanding the functional mechanisms of RHOA can provide valuable insights into the intricate molecular processes underlying cell physiology and pathogenesis.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
25.7 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The RHOA solution (1 mg/ml) 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAA IRKKLVIVGD GACGKTCLLI VFSKDQFPEV YVPTVFENYV ADIEVDGKQV ELALWDTAGQ EDYDRLRPLS YPDTDVILMC FSIDSPDSLE NIPEKWTPEV KHFCPNVPII LVGNKKDLRN DEHTRRELAK MKQEPVKPEE GRDMANRIGA FGYMECSAKT KDGVREVFEM ATRAALQARR GKKKSGC.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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RHOA

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