RGS21

Alternative Names: RGS21, Regulator of G-protein signaling 21

RGS21 is a regulatory molecule that belongs to the RGS family. It acts as a GTPase activating protein for G alpha subunits of heterotrimeric G proteins, inhibiting signal transduction. By increasing the GTPase activity of G protein alpha subunits, RGS21 drives them into their inactive GDP-bound form.

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  • Sku: PSB-pro-898-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Regulator of G-Protein Signaling 21 (RGS21) is a protein that belongs to the RGS protein family. RGS proteins play a critical role in regulating G-protein signaling pathways, which are involved in various cellular processes. RGS21 has a molecular weight of approximately X kilodaltons (kDa), making it a relatively small protein. By modulating the activity of G-proteins, RGS21 contributes to the fine-tuning of signaling cascades, thereby influencing cellular responses. Its precise functions and mechanisms of action are still under investigation, but its importance in G-protein signaling regulation cannot be overstated.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
20.2 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation SCRN1 protein solution (0.5mg/ml) containing Phosphate buffered saline (pH7.4) , 10% glycerol and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMPVKCC FYRSPTAETM TWSENMDTLL ANQAGLDAFR IFLKSEFSEE NVEFWLACED FKKTKNADKI ASKAKMIYSE FIEADAPKEI NIDFGTRDLI SKNIAEPTLK CFDEAQKLIY CLMAKDSFPR FLKSEIYKKL VNSQQVPNHK KWLPFL.

Storage Instruction

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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RGS21

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