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rGRO g CINC-2a

Alternative Names: Cytokine-induced neutrophil chemoattractant 2, CINC-2, CINC2, Macrophage inflammatory protein 2-alpha.

The cytokine CXCL3, also known as GRO3, GROg, and MIP2b, is a small molecule that belongs to the CXC chemokine family. It plays a role in controlling the migration and adhesion of monocytes by interacting with a cell surface receptor called CXCR2. The gene for CXCL3 is found on chromosome 4, along with other CXC chemokines.

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  • Sku: PSB-chm-258-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Rat GRO-gamma (CXCL3), CINC-2 alpha is a protein belonging to the chemokine family. With a molecular weight of approximately X kDa, this protein plays a significant role in immune response and inflammation regulation. It acts as a chemoattractant for neutrophils and other immune cells, facilitating their migration to sites of infection or tissue damage. Recombinant Rat GRO-gamma (CXCL3), CINC-2 alpha is widely used in scientific research to study the mechanisms involved in immune system functioning and to develop potential therapeutic interventions for inflammatory diseases.

Current Lead Time

7-14 Days

Product Specifications

Species
 Rat
Expression System E. coli
Purity 98% by SDS-PAGE
Activity
 Determined by its ability to chemoattract 293 transfected CXCR2 cells using a concentration range of 10-100 ng/ml, corresponding to a specific activity of 10,000-100,000 units/mg. Determined by its ability to chemoattract 293 transfected CXCR2 cells using a concentration range of 10-100 ng/ml, corresponding to a specific activity of 10,000-100,000 units/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Monomer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation The Rat CXCL3 lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

RELRCQCLKT LPRVDFENIQ SLTVTPPGPH CTQTEVIATL KDGQEVCLNP QAPRLQKIIQ KLLKSDKSS.

Storage Instruction

Lyophilized GRO-gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL3 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Sample Prep Instruction

It is recommended to reconstitute the lyophilized GRO-gamma in sterile 18Mcm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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rGRO g CINC-2a
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