rGRO a

Alternative Names: Growth-regulated protein alpha, GRO-alpha(1-73), GRO1, GROa, CXCL1, chemokine (C-X-C motif) ligand 1, Melanoma growth stimulatory activity, MGSA, MGSA-a, MGSA alpha, Neutrophil-activating protein 3, NAP-3, SCYB1.

CXCL1, a member of the CXC chemokine family, is a cytokine with various names including GRO1 oncogene, NAP-3, and MSGA-α. It is produced by human melanoma cells and is involved in melanoma progression. This chemokine attracts neutrophils and is implicated in spinal cord development, angiogenesis, inflammation, wound healing, and tumorigenesis. CXCL1 signals through the CXCR2 receptor and is located on human chromosome 4 with other CXC chemokine genes.

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  • Sku: PSB-chm-375-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Rat GRO-alpha (CXCL1) is a member of the CXC chemokine family, known for its role in inflammation and immune response regulation. This protein weighs approximately 8.3 kDa and is commonly used in research settings to study chemotaxis, angiogenesis, and cell migration. Recombinant Rat GRO-alpha is produced through genetic engineering techniques, allowing for consistent and high-quality protein production for experimental use.

Current Lead Time

7-14 Days

Product Specifications

Species
 Rat
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
 Determined by its ability to chemoattract rat neutrophils using a concentration range of 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg. Determined by its ability to chemoattract rat neutrophils using a concentration range of 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Lyophilized from a 0.2μm filtered concentrated (1mg/ml) solution in 20mM PB, pH 7.4, and 150mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK.

Storage Instruction

Lyophilized CXCL1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL1 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized CXCL1 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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rGRO a
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