rFGF18

Alternative Names: Fibroblast growth factor 18, FGF-18, Fgf18, zFGF5, D130055P09Rik.

Fibroblast growth factor 18 (FGF18) is part of a large family of growth factors called FGFs. FGF18 plays a crucial role in the development of long bones and the calvarium. It signals through receptors known as FGFR 1c, 2c, 3c, and 4. FGFs have a common structure consisting of a 120 amino acid FGF domain. They are expressed during embryonic development and in specific adult tissues.

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  • Sku: PSB-cyt-176-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Rat Fibroblast Growth Factor-18 (FGF-18) is a protein belonging to the fibroblast growth factor family. With a molecular weight of approximately 18 kDa, FGF-18 plays a significant role in various biological processes, including embryonic development, tissue repair, and cell proliferation. This recombinant protein is synthesized through genetic engineering techniques, ensuring its purity and consistency. Its potential applications in research and therapeutic interventions make Recombinant Rat FGF-18 a valuable tool for investigating cellular mechanisms and developing novel treatments.

Current Lead Time

7-14 Days

Product Specifications

Species
Rat
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is < 0.5ng/ml, corresponding to a specific activity of > 2.0×1,000,000 units/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
21.0 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation Lyophilized from a 0.2um filtered concentrated solution in PBS and 0.5M NaCl, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

EENVDFRIHV ENQTRARDDV SRKQLRLYQL YSRTSGKHIQ VLGRRISARG EDGDKYAQLL VETDTFGSQV RIKGKETEFY LCMNRKGKLV GKPDGTSKEC VFIEKVLENN YTALMSAKYS GWYVGFTKKG RPRKGPKTRE NQQDVHFMKR YPKGQTELQK PFKYTTVTKR SRRIRPTHPG

Storage Instruction

Lyophilized FGF 18 Rat although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FGF 18 Rat should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized FGF 18 in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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rFGF18

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