RASSF3

Alternative Names: RASSF3, Ras association domain-containing protein 3.

Ras association domain-containing protein 3 (RASSF3) is an extensively present protein in both normal and cancerous tissues. As a member of the RASSF family, RASSF3 shares a Ras association domain (Ral GDS/AF-6 or RA) with other members and acts as a suppressor of Ras effects and tumors. RASSF3 consists of an N-terminal RA domain and a coiled-coil SARAH domain, and it may have three different isoforms (RASSF3A, RASSF3B, and RASSF3C) due to alternative splicing. However, RASSF3B and RASSF3C are shorter versions of RASSF3A and lack the RA and SARAH domains.

  •
  • Sku: PSB-pro-1378-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Ras Association Domain-Containing Protein 3 (RASSF3) is a member of the Ras Association Domain (RASSF) family, which plays a significant role in regulating cell growth, apoptosis, and cell cycle progression. RASSF3 is a protein with a molecular weight of approximately X kDa (insert specific weight). It functions as a tumor suppressor by modulating various signaling pathways involved in cell proliferation and differentiation. This protein is involved in multiple cellular processes and its dysregulation has been implicated in various human cancers. Understanding the molecular mechanisms and functions of RASSF3 can provide valuable insights into the development of novel therapeutic strategies for cancer treatment.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation RASSF3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSSGYSS LEEDAEDFFF TARTSFFRRA PQGKPRSGQQ DVEKEKETHS YLSKEEIKEK VHKYNLAVTD KLKMTLNSNG IYTGFIKVQM ELCKPPQTSP NSGKLSPSSN GCMNTLHISS TNTVGEVIEA LLKKFLVTES PAKFALYKRC HREDQVYACK LSDREHPLYL RLVAGPRTDT LSFVLREHEI GEWEAFSLPE LQNFLRILDK EEDEQLQNLK RRYTAYRQKL EEALREVWKP D.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
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References

Not Available
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RASSF3
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