RARRES2, Sf9

Alternative Names: Not Available

RARRES2 is a chemotactic protein that induces chemotaxis via the ChemR23 G protein-coupled receptor. It is upregulated by tazarotene and is found in various tissues. RARRES2 acts as an adipokine and is structurally similar to other proteins such as cystatin C and kininogens. It promotes calcium mobilization and chemotaxis in immature dendritic cells and macrophages. RARRES2 is initially secreted with low activity and requires proteolytic cleavage to become a potent agonist of ChemR23. It signals through the ChemR23 receptor to regulate adipocyte differentiation and metabolic function. Additionally, the ChemR23 receptor acts as a coreceptor for some strains of SIV and primary HIV-1. Another ligand for the ChemR23 receptor is tazarotene-induced gene.

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  • Sku: PSB-pro-2382-1µg
  • Vendor: ProSpec-Tany
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Product Details

Product Description

Recombinant Human Retinoic Acid Receptor Responder 2, Sf9 is a protein belonging to the retinoic acid receptor family. With a molecular weight of approximately [insert weight], this protein plays a significant role in cellular processes by binding to retinoic acid and regulating gene expression. As a member of the retinoic acid receptor family, Recombinant Human Retinoic Acid Receptor Responder 2, Sf9 is involved in various biological functions, including development, differentiation, and homeostasis. Its precise mechanism of action and interaction with other molecules make it a subject of interest in scientific research and drug discovery.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System Sf9 - Baculovirus cells
Purity 90% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 16.9 kDa
Structure Monomer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation RARRES2 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ADPELTEAQR RGLQVALEEF HKHPPVQWAF QETSVESAVD TPFPAGIFVR LEFKLQQTSC RKRDWKKPEC KVRPNGRKRK CLACIKLGSE DKVLGRLVHC PIETQVLREA EEHQETQCLR VQRAGEDPHS FYFPGQFAFS HHHHHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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RARRES2, Sf9
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