RARRES2, HEK

Alternative Names: Chemerin, TIG2, Tazarotene-induced gene 2 protein, Retinoic acid receptor responder protein 2, RAR-responsive protein TIG2, RARRES2, HP10433. Reordered series: HP10433, Chemerin, TIG2, Tazarotene-induced gene 2 protein, Retinoic acid receptor responder protein 2, RAR-responsive protein TIG2, RARRES2.

RARRES2, a chemotactic protein, induces chemotaxis through the ChemR23 G protein-coupled receptor. It is upregulated by tazarotene, a synthetic retinoid, and is present in various tissues. Acting as an adipokine, RARRES2 is a truncated proprotein related to cathelicidin precursors, cystatin C, and kininogens. It stimulates calcium mobilization and chemotaxis of immature dendritic cells and macrophages. However, RARRES2 initially exhibits low biological activity and requires proteolytic cleavage of its COOH-terminal domain to become a potent and highly specific agonist of ChemR23.

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  • Sku: PSB-pro-2596-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Retinoic Acid Receptor Responder 2, HEK, is a protein that belongs to the retinoic acid receptor (RAR) family. With a molecular weight of approximately X kDa, this protein plays a significant role in cellular processes regulated by retinoic acid signaling pathways. It acts as a transcription factor, modulating gene expression and participating in the regulation of various biological functions. The Recombinant Human Retinoic Acid Receptor Responder 2, HEK, protein is widely studied for its involvement in developmental processes, cell differentiation, and homeostasis maintenance, making it a valuable tool for research in the field of molecular biology and genetics.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System HEK 293
Purity 90.0 by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
 16.6 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation RARRES2 protein solution (0.5mg/ml) contains 10% glycerol & Phosphate buffered saline (pH7.4).

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ELTEAQRRGL QVALEEFHKH PPVQWAFQET SVESAVDTPF PAGIFVRLEF KLQQTSCRKR DWKKPECKVR PNGRKRKCLA CIKLGSEDKV LGRLVHCPIE TQVLREAEEH QETQCLRVQR AGEDPHSFYF PGQFAFSHHH HHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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RARRES2, HEK
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