Rantes

Alternative Names: Small inducible cytokine A5, SCYA5, chemokine (C-C motif) ligand 5, CCL5, T-cell-specific RANTES protein, RANTES, T cell-specific protein P228, TCP228, SIS-delta, SISd, T cell-specific protein P228, D17S136E, MGC17164.

RANTES, now known as CCL5, is a chemokine that is 8 kDa in size. It is responsible for attracting T cells, eosinophils, and basophils to sites of inflammation. Additionally, RANTES can stimulate the proliferation and activation of certain natural killer cells when combined with specific cytokines such as IL-2 and IFN-g. It is also known to suppress HIV and is located on chromosome 17 in humans.

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  • Sku: PSB-chm-328-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Rantes (CCL5) is a chemokine belonging to the CC family. It plays a key role in immune responses by attracting and activating various immune cells. With a molecular weight of approximately 8.8 kDa, Recombinant Human Rantes is commonly used in research studies to investigate its effects on inflammation and immune system regulation.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
The Rantes activity is determined by the chemoattract of human blood monocytes at a concentration between 1-10ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg. The Rantes activity is determined by the chemoattract of human blood monocytes at a concentration between 1-10ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation Lyophilized from a 0.2µm filtered concentrated solution in 50mM NaAc, pH 5.0, 100mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS.

Storage Instruction

Lyophilized Rantes although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Rantes should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Rantes in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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Rantes

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