RANBP3

Alternative Names: RanBP3, RAN binding protein 3.

RANBP3 is a protein present in both the nucleus and cytoplasm. It plays a role in nuclear export through its RanBD1 domain in collaboration with other proteins. Additionally, RANBP3 interacts with SMAD2 and SMAD3 proteins to inhibit TGF-beta signaling.

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  • Sku: PSB-pro-1986-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human RAN Binding Protein 3, a member of the RANBP protein family, is a vital component involved in various cellular processes. This protein, with a molecular weight of X kDa, plays a significant role in nucleocytoplasmic transport, cell cycle progression, and mitotic spindle assembly. It functions by interacting with the small GTPase RAN and regulating its activity, thereby facilitating the transport of macromolecules across the nuclear envelope. Understanding the intricate mechanisms and functions of Recombinant Human RAN Binding Protein 3 is crucial for comprehending fundamental cellular processes.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
25.5 kDa
Structure Heteromer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation RANBP3 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSISSSLEN STNSADASSN KFVFGQNMSE RVLSPPKLNE VSSDANRENA AAESGSESSS QEATPEKESL AESAAAYTKA TARKCLLEKV EVITGEEAES NVLQMQCKLF VFDKTSQSWV ERGRGLLRLN DMASTDDGTL QSRLVMRTQG SLRLILNTKL WAQMQIDKAS EKSIRITAMD TEDQGVKVFL ISASSKDTGQ LYAALHHRIL ALRS.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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RANBP3

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