RAET1E, Sf9

Alternative Names: BA350J20.7, Lymphocyte Effector Toxicity Activation Ligand, N2DL-4, N2DL4, NKG2D Ligand 4, NKG2DL4, RAET1E2, RAE-1-Like Transcript 4, Retinoic Acid Early Transcript 1E, RL-4, ULBP4

RAET1E is a member of the MHC class I family, which consists of MHC class I-related genes located on chromosome 6q24.2-q25.3. Unlike other RAET1 proteins, RAET1E and RAET1G proteins have type I membrane-spanning sequences at their C termini instead of glycosylphosphatidylinositol anchor sequences. RAET1E binds to the NKG2D receptor, which is expressed on various immune cells and is involved in both innate and adaptive immune responses. This interaction allows RAET1E to send signals to NK cells and promote tumor immune surveillance by stimulating the growth of anti-tumor cytotoxic lymphocytes.

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  • Sku: PSB-pro-2467-1µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Retinoic Acid Early Transcript 1E, Sf9 is a protein that belongs to the retinoic acid early transcript 1 (RAET1) family. This protein, with a molecular weight of [insert weight], plays a significant role in various cellular processes. It is involved in immune surveillance and regulation, particularly in the recognition and elimination of abnormal cells. By interacting with natural killer (NK) cells and T lymphocytes, Recombinant Human Retinoic Acid Early Transcript 1E, Sf9 contributes to the modulation of immune responses. Its precise functions and mechanisms are subjects of ongoing scientific investigation.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System Sf9 - Baculovirus cells
Purity 90.0 % by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 23.4 kDa
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation RAET1E protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ADPHSLCFNF TIKSLSRPGQ PWCEAQVFLN KNLFLQYNSD NNMVKPLGLL GKKVYATSTW GELTQTLGEV GRDLRMLLCD IKPQIKTSDP STLQVEMFCQ REAERCTGAS WQFATNGEKS LLFDAMNMTW TVINHEASKI KETWKKDRGL EKYFRKLSKG DCDHWLREFL GHWEAMPEPT VSPVNASDIH WSSSSLPDHH HHHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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RAET1E, Sf9
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