RAC2 (189)

Alternative Names: Small G protein, RAC2, Ras-related C3 botulinum toxin substrate 2, p21-Rac2, GX, HSPC022, EN-7.

RAC2 is a small signaling G protein/GTPase that belongs to the RAS superfamily. It is involved in various cellular processes, including cell growth, actin cytoskeletal organization, cell proliferation, survival, cell cycle progression, gene transcription regulation, and the activation of protein kinases. RAC2 switches between an active gtp-bound state and an inactive gdp-bound state. In its active state, RAC2 binds to different effector proteins to control cellular responses such as secretion, phagocytosis of apoptotic cells, and epithelial cell polarization. Moreover, RAC2 plays a role in regulating the nadph oxidase.

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  • Sku: PSB-pro-719-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Ras-Related C3 Botulinum Toxin Substrate 2 (1-189) is a protein that belongs to the Ras GTPase family. With a molecular weight of approximately X kDa, it serves as a crucial signaling molecule involved in various cellular processes. This recombinant protein is commonly utilized in scientific research to investigate the intricate mechanisms underlying cellular signaling pathways. Its structural and functional properties make it a valuable tool for studying the regulation and modulation of Ras-related processes, contributing to a deeper understanding of cellular physiology.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 23.3 kDa
Structure Monomer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The RAC2 solution contains 20mM Tris-HCl buffer (pH 8.0), 20% Glycerol, 2mM EDTA, 2mM DTT and 0.1M NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDSKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASY ENVRAKWFPE VRHHCPSTPI ILVGTKLDLR DDKDTIEKLK EKKLAPITYP QGLALAKEID SVKYLECSAL TQRGLKTVFD EAIRAVLCPQ PTRQQKRAC.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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RAC2 (189)
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