RAB6B

Alternative Names: Anaphase-promoting complex subunit 13, APC13, ANAPC13, Cylosome subunit 13, SWM1.

ANAPC13 is a vital component of the anaphase promoting complex that plays a crucial role in regulating cell cycle progression. It functions primarily by facilitating the degradation of certain cell cycle regulators, such as B-type cyclins. ANAPC13 is a conserved protein that is essential for maintaining the integrity and functioning of the anaphase promoting complex's ubiquitin ligase activity.

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  • Sku: PSB-pro-103-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human RAB6B, a member of the RAS oncogene family, is a protein that plays a significant role in intracellular vesicle trafficking and protein transport. Belonging to the small GTPase superfamily, RAB6B regulates the movement of vesicles between the Golgi apparatus and the endoplasmic reticulum, thereby contributing to the maintenance of cellular homeostasis. With a molecular weight of approximately X kilodaltons, this protein is involved in various cellular processes, including protein sorting, membrane fusion, and organelle organization. Its precise functions make Recombinant Human RAB6B an important target for studying intracellular transport mechanisms and potential therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The ANAPC13 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 1mM DTT and 0.1M NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MASMTGGQQM GRGSHMDSEV QRDGRILDLI DDAWREDKLP YEDVAIPLNE LPEPEQDNGG TTESVKEQEM KWTDLALQYL HENVPPIGN.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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RAB6B

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