RAB5C

Alternative Names: L1880, RAB5CL, RAB5L, RABL, RAB5C, Ras-related protein Rab-5C.

RAB5C, a member of the Ras-related protein family, is a small GTPase that plays a vital role in ensuring the reliable docking and fusion of vesicles with their respective acceptor compartments.

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  • Sku: PSB-pro-1427-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human RAB5C, a member of the RAS oncogene family, is a protein that plays a significant role in intracellular vesicle trafficking and endocytosis. Belonging to the small GTPase superfamily, RAB5C regulates the fusion of early endosomes and is involved in the transport of cargo molecules from the plasma membrane to early endosomes. With a molecular weight of approximately X kDa, this protein is crucial for maintaining cellular homeostasis and proper functioning of various cellular processes.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
25.9 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The RAB5C solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 30% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAGRGGA ARPNGPAAGN KICQFKLVLL GESAVGKSSL VLRFVKGQFH EYQESTIGAA FLTQTVCLDD TTVKFEIWDT AGQERYHSLA PMYYRGAQAA IVVYDITNTD TFARAKNWVK ELQRQASPNI VIALAGNKAD LASKRAVEFQ EAQAYADDNS LLFMETSAKT AMNVNEIFMA IAKKLPKNEP QNATGAPGRN RGVDLQENNP ASRSQCCSN.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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RAB5C

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