RAB23

Alternative Names: RAB23 member RAS oncogene family, RAB family small GTP binding protein RAB 23, ras-related protein Rab-23, HSPC137.

RAB23 is a member of the Rab family of proteins and is located in the cytoplasmic side of the cell membrane. It plays a role in protein transportation within the cell and signal transduction mediated by small GTPases. RAB23 acts as an important regulator of the Sonic hedgehog signaling pathway. Mutations in the gene encoding RAB23 are responsible for Carpenter syndrome, a disorder associated with obesity, cardiac defects, polysyndactyly, and craniosynostosis.

  •
  • Sku: PSB-pro-977-5µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human RAB23, Member RAS Oncogene Family is a protein that belongs to the RAS oncogene family. This protein plays a crucial role in regulating intracellular vesicular trafficking and protein transport. With a weight of approximately 23 kDa, it functions as a molecular switch, controlling the trafficking of various cargo proteins between different cellular compartments. Understanding the precise mechanisms and functions of Recombinant Human RAB23 is of great significance in unraveling the complex cellular processes associated with vesicular trafficking and protein sorting.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The RAB23 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 0.1mM PMSF and 30% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MLEEDMEVAI KMVVVGNGAV GKSSMIQRYC KGIFTKDYKK TIGVDFLERQ IQVNDEDVRL MLWDTAGQEE FDAITKAYYR GAQACVLVFS TTDRESFEAV SSWREKVVAE VGDIPTVLVQ NKIDLLDDSC IKNEEAEALA KRLKLRFYRT SVKEDLNVNE VFKYLAEKYL QKLKQQIAED PELTHSSSNK IGVFNTSGGS HSGQNSGTLN GGDVINLRPN KQRTKKNRNP FSSC

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
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References

Not Available
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RAB23
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