RAB1B

Alternative Names: RAB1B, Ras-related protein Rab-1B

RAB1B is a member of the RAB protein family, which are small GTPases found on the cytoplasmic surfaces of specific membrane-bound organelles. This protein plays a crucial role in the early secretory pathway by facilitating vesicle transport between the endoplasmic reticulum (ER) and Golgi.

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  • Sku: PSB-pro-045-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human RAB1B, Member RAS Oncogene Family is a protein that belongs to the RAS oncogene family. With a weight of approximately X kDa, this protein plays a significant role in intracellular vesicle trafficking and protein transport. It is involved in the regulation of various cellular processes, including exocytosis, endocytosis, and autophagy. As a small GTPase, RAB1B functions as a molecular switch, cycling between an active GTP-bound state and an inactive GDP-bound state, thereby controlling the movement of vesicles between different compartments within the cell. Understanding the precise mechanisms and functions of RAB1B in cellular processes is of great importance for elucidating various pathological conditions and developing potential therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
24.3 kDa
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The RAB1B solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0) and 10% Glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MNPEYDYLFK LLLIGDSGVG KSCLLLRFAD DTYTESYIST IGVDFKIRTI ELDGKTIKLQ IWDTAGQERF RTITSSYYRG AHGIIVVYDV TDQESYANVK QWLQEIDRYA SENVNKLLVG NKSDLTTKKV VDNTTAKEFA DSLGIPFLET SAKNATNVEQ AFMTMAAEIK KRMGPGAASG GERPNLKIDS TPVKPAGGGC C.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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RAB1B

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