RAB14

Alternative Names: small GTP binding protein RAB14, RAB14 member RAS oncogene family, ras-related protein Rab-14, F protein-binding protein 1, bA165P4.3 (member RAS oncogene family), FBP

RAB14 is a low molecular mass monomeric GTPase protein belonging to the RAB family. It is found on the cytoplasmic surfaces of specific membrane bound organelles. RAB14 plays a role in vesicular trafficking and neurotransmitter release in various parts of the body. It is highly expressed in the brain, lung, kidney, spleen, and thymus. Additionally, RAB14 is involved in the biosynthetic/recycling pathway between the Golgi and endosomal compartments.

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  • Sku: PSB-pro-873-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human RAB14, Member RAS Oncogene Family is a protein that belongs to the RAS oncogene family. With a weight of approximately X kDa, this protein plays a significant role in intracellular vesicle trafficking and membrane dynamics. It is involved in regulating endocytic recycling pathways, which are crucial for maintaining cellular homeostasis. Through its interactions with various effector proteins, RAB14 contributes to the proper sorting and transport of cargo molecules within the cell. Understanding the functions and mechanisms of RAB14 can provide valuable insights into cellular processes and potential therapeutic targets.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation RAB14 protein 0.5mg/ml is supplied in 20mM Tris-HCL, pH-8, 0.1M NaCl, 1mM DTT and 20% Glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMATAPYN YSYIFKYIII GDMGVGKSCL LHQFTEKKFM ADCPHTIGVE FGTRIIEVSG QKIKLQIWDT AGQERFRAVT RSYYRGAAGA LMVYDITRRS TYNHLSSWLT DARNLTNPNT VIILIGNKAD LEAQRDVTYE EAKQFAEENG LLFLEASAKT GENVEDAFLE AAKKIYQNIQ DGSLDLNAAE SGVQHKPSAP QGGRLTSEPQ PQREGCGC

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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RAB14

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