PTX3 HEK

Alternative Names: TSG-14, TNFAIP5, PTX3, TSG14, Pentraxin-related protein PTX3, Pentaxin-related protein PTX3, Tumor necrosis factor-inducible gene 14 protein, pentraxin-related gene rapidly induced by IL-1 beta.

PTX3, a member of the pentraxin family, has a unique structure consisting of a C-terminal domain shared with short pentraxins and a distinct N-terminal domain. It is produced and released at sites of inflammation by various cell types, including monocytes/macrophages, endothelial cells, vascular smooth muscle cells, fibroblasts, and adipocytes. PTX3 plays a role in innate resistance to pathogens, regulation of inflammatory reactions, potential clearance of self-components, and female fertility. Moreover, it serves as a marker for disease activity in psoriasis, with higher serum levels indicating greater severity. Additionally, elevated serum levels of PTX3 have been linked to the severity of systemic sclerosis and indicate the presence of pulmonary fungal infections.

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  • Sku: PSB-pro-2041-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Pentraxin-3, HEK, is a protein belonging to the pentraxin family. With a molecular weight of approximately [insert weight], it plays a significant role in the immune response and inflammatory processes. This recombinant protein is produced using human embryonic kidney (HEK) cells, ensuring high purity and biological activity. Its importance lies in its ability to modulate innate immunity, regulate vascular inflammation, and promote tissue repair. The Recombinant Human Pentraxin-3, HEK, serves as a valuable tool for researchers investigating the intricate mechanisms underlying immune responses and inflammatory disorders.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System HEK 293
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation PTX3 was filtered (0.4 µm) and lyophilized from 0.5mg/ml solution in phosphate buffered saline.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ENSDDYDLMY VNLDNEIDNG LHPTEDPTPC DCGQEHSEWD KLFIMLENSQ MRERMLLQAT DDVLRGELQR LREELGRLAE SLARPCAPGA PAEARLTSAL DELLQATRDA GRRLARMEGA EAQRPEEAGR ALAAVLEELR QTRADLHAVQ GWAARSWLPA GCETAILFPM RSKKIFGSVH PVRPMRLESF SACIWVKATD VLNKTILFSY GTKRNPYEIQ LYLSYQSIVF VVGGEENKLV AEAMVSLGRW THLCGTWNSE EGLTSLWVNG ELAATTVEMA TGHIVPEGGI LQIGQEKNGC CVGGGFDETL AFSGRLTGFN IWDSVLSNEE IRETGGAESC HIRGNIVGWG VTEIQPHGGA QYVSHHHHHH.

Storage Instruction

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Sample Prep Instruction

It is recommended to add deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. PTX3 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

References

Not Available

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PTX3 HEK

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